Transforming the virology landscape and establishing human organoids as superior models for virus research.
OrganoVIR Labs, based in Amsterdam University Medical Centers (location Academic Medical Center (AMC)), is an expert laboratory on virus culture and human 2D and 3D ‘organoid cultures’ for virology.
An ‘organoid’ is a miniature and simplified version of a human organ. An organoid contains the DNA of its donor, which means that it carries the personal characteristics of that donor (such as genetic make-up, age, gender, etc.). This makes them the ideal model to study viral infections in a human context.
Currently, there are not enough suitable experimental models to study human viral infections. Animal models or conventional 2-dimensional (2D) cell cultures do not accurately translate to human infections. However, data collected from our labs have shown that results obtained with human organoid models translate well to human diseases. This is because infections of human organoid cultures provide more accurate information of how viruses infect human cells.