Pamela Capendale is a PhD candidate at the OrganoVIR Labs at the Amsterdam UMC location AMC. She has a B.Sc. In Biomedical Sciences and M.Sc. In Biofabrication, specialized in tissue engineering. During her PhD Pamela aims to develop a Blood Brain Barrier-Brain in vitro model for virology studies using iPSC derived brain cells and organoids. This project is part of the Focus-on-Virus Project which is set up in collaboration with the Department of Experimental Immunology of the Amsterdam UMC, location AMC. The viruses Pamela specifically focuses on are Parechovirus (PeV-A) and Human Immunodeficiency Virus (HIV-1). By establishing these complex BBB-Brain models Pamela hopes to help get more insight in the infectious behavior of these viruses in vivo.
Amsterdam University Medical Centers (Amsterdam UMC) is one of the foremost research institutions in the Netherlands and one of its largest hospitals, with 1500 staff members employed in medical research. The Amsterdam UMC research is organized in 7 themes within the AMC Research Institute, where AMC Principal Investigators (PIs) are appointed to develop their own research lines. The AMC Graduate School organizes doctorate level academic training of AMC PhD students (209 PhD rewarded in 2016). This concentration of expertise makes the center a breeding ground for fruitful scientific collaborations.